A study published in the September 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that children and adolescents diagnosed with a psychiatric diagnosis had an increased risk of developing diabetes if they were exposed to antipsychotics.
Using data from the nationwide Danish registers, a group of researchers led by Dr. RenÉ Ernst Nielsen, Psychiatry, Aalborg University Hospital, Denmark, studied 48,299 children and adolescents with psychiatric disorders to document the frequency and possible predictors of type II diabetes, defined by treatment with an oral antidiabetic drug.
The study found that the absolute risk of diabetes in psychiatrically ill youth exposed to antipsychotic medications was approximately 0.72% compared to 0.27% in those not exposed to antipsychotics. Especially female sex and antipsychotic drug exposure increased the risk of developing type II diabetes, while type of psychiatric diagnosis was not related to diabetes development.
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