Racial Discrimination and Resting-State Functional Connectivity of Salience Network Nodes in Trauma-Exposed Black Adults in the United States [jamanetwork.com]

Rafael Maravilla(PACEs Connection Staff) 1/27/2212:16 PM

By E. Kate Webb, Claire M. Bird, Terri A. deRoon-Cassini, et al., Image: Unsplash, JAMA Network Open, January 24, 2022

Key Points

Question Are experiences of racial discrimination associated with altered resting-state connectivity patterns of salience network nodes?

Findings In this cross-sectional study of 102 Black adults, more experiences of racial discrimination were associated with altered connectivity of the amygdala and anterior insula, even after adjusting for annual household income, lifetime trauma exposure, and current posttraumatic stress disorder symptoms.

Meaning These findings suggest that experiencing racial discrimination is associated with modifications to known neural correlates of vigilance, suggesting a viable mechanism by which racism negatively affects mental health.

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