The weight-regulating hormones leptin and irisin were elevated whileadiponectin was decreased in people who experienced higher levels or repeated incidents of physical, emotional or sexual abuse or neglect as children, according to new research.
"What we are seeing is a direct correlation between childhood adversity and hormone impairment, over and above the impact abuse or neglect may have on lifestyle factors such as diet and education,"Christos S. Mantzoros, MD, DSc, PhD, of Beth Israel Deaconess Medical Center and the VA Boston Healthcare System, said in a press release.
In the cross-sectional study, a racially diverse group of 95 participants (mean age, 45.7 years) were separated into three groups based on the level of trauma or adversity experienced as a child. There were no significant differences in physical activity or diet between the groups, but BMI was higher in the group that experienced the highest amount of childhood trauma. Blood samples were collected from participants to measure leptin, irisin, C-reactive protein and adiponectin.
Childhood trauma linked to weight-regulating hormones
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