[Editor's note: Dr. Harise Stein at Stanford University edits a web site -- abuseresearch.info -- that focuses on the health effects of abuse, and includes research articles on ACEs. Every month, she will post the summaries of the abstracts and links to research articles that address only ACEs. Thank you, Harise!! -- Jane Stevens]
Quinn K, Boone L, Scheidell JD, et. al.
The relationships of childhood trauma and adulthood prescription pain reliever misuse and injection drug use.
Drug Alcohol Dep. 2016 Dec 1;169:190-198.PMID: 27816251
From a large national study of adolescent and adult health, “A strong and consistent dose-response relationship emerged” for prescription pain reliever misuse drug outcomes and cumulative trauma.
Thurston RC, Chang Y, Barinas-Mitchell E, et. al.
Child Abuse and Neglect and Subclinical Cardiovascular Disease Among Midlife Women.
Psychosom Med. 2017 May;79(4):441-449. PMID: 27763988
For 346 mid-life community women, despite controlling for a large number of variables, a history of childhood abuse or neglect was associated with subclinical cardiovascular disease, measured by thickening of the carotid artery (intima media thickness = IMT). Sleep disturbance and hot flashes increased this relationship.
Briere J, Agee E, Dietrich A.
Cumulative trauma and current posttraumatic stress disorder status in general population and inmate samples.
Psychol Trauma. 2016 Jul;8(4):439-46. PMID: 26752099
Comparing datasets from the general population and prison samples, PTSD was found in 4% of the general population and 48% of the prison sample. In the prison sample, women reported 70% childhood sexual abuse and men reported 50%. For the community sample, those with 6 or more trauma types had a 12% likelihood of PTSD, while for the prison sample 6+ exposure had a 64% chance of PTSD.
Etain B, Lajnef M, Brichant-Petitjean C, et. al.
Childhood trauma and mixed episodes are associated with poor response to lithium in bipolar disorders.
Acta Psychiatr Scand. 2017 Apr;135(4):319-327. PMID: 27987204
Of 148 bipolar patients, those exposed to at least two childhood trauma abuses, compared to none, were 4.9 times less likely to respond to lithium.
Naramore R, Bright MA, Epps N, Hardt NS.
Youth Arrested for Trading Sex Have the Highest Rates of Childhood Adversity: A Statewide Study.
Sex Abuse. 2017 Jun;29(4):396-410. PMID: 26337192
For over 64,000 arrested Florida youth, those related to sex trafficking had higher # of ACEs, and higher rates of ACEs, particularly a history of sexual abuse or physical neglect.
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