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PACEs in Medical Schools


Association Between Depressive Symptoms and Incident Cardiovascular Diseases (JAMA)

Eric L. Harshfield, PhD 1,2 ; Lisa Pennells, PhD 1 ; Joseph E. Schwartz, PhD 3,4 ; et al December 15, 2020, JAMA. 2020;324(23):2396-2405. doi:10.1001/jama.2020.23068 Abstract Importance It is uncertain whether depressive symptoms are independently associated with subsequent risk of cardiovascular diseases (CVDs). Objective To characterize the association between depressive symptoms and CVD incidence across the spectrum of lower mood. Design, Setting, and Participants A pooled analysis of...

Synergistic adversities and behavioral problems in traumatized children and adolescents (Child Abuse & Neglect)

By Frank W. Putnam a Ernestine C. Briggs b . Abstract Objective This study investigated synergy of commonly co-occurring pairs of childhood traumas/adversities to determine: 1) if synergistic pairings differ by gender and/or age grouping; and 2) if some traumas/adversities were more synergistically reactive. Methods A sample of 10,355 clinic-referred youth (1.5–18 years) from the National Child Traumatic Stress Network Core Data Set was divided by...

Association of Early-Life Adversity With Measures of Accelerated Biological Aging Among Children in China (JAMA)

By: Ying Sun, MD; Jiao Fang, MS; Yuhui Wan, MD; Puyu Su, MD; Fangbiao Tao, MD. JAMA Netw Open. 2020; 3(9):e2013588. doi: 10.1001/jamanetworkopen.2020.13588 Key Points Question Aretheredimension-and sex-specific longitudinal associations between early-life adversity and accelerated biological aging in children with specific genetic backgrounds? Findings Thiscohortstudyof997 youths found that both threat- and deprivation-related early-life adversity were associated with earlier age of pubertal...

Free 2020 Virtual Trauma-Informed Care Conference

Each year, STAR hosts a Trauma-Informed Care Conference to help educate the next generation of leaders and build a strong network of Trauma-Informed professionals in the state of Georgia. The conference will be held on Saturday, October 3rd from 10:00am- 1:00pm EST and Sunday, October 4th , 2020 from 2:00pm-5:00pm EST conducted virtually via Zoom.

Researchers discover a specific brain circuit damaged by social isolation during childhood (Science Direct)

August 31, 2020, The Mount Sinai Hospital / Mount Sinai School of Medicine. Study in mice shows long-lasting effects and points the way to potential treatments Summary: Researchers have identified specific sub-populations of brain cells in the prefrontal cortex, a key part of the brain that regulates social behavior, that are required for normal sociability in adulthood and are profoundly vulnerable to juvenile social isolation in mice. [ Please click here to read more. ]

Cost-effectiveness of Leveraging Social Determinants of Health to Improve Breast, Cervical, and Colorectal Cancer Screening (JAMA)

By Giridhar Mohan, MPH; Sajal Chattopadhyay PhD., JAMA Oncol. Published online June 18, 2020. doi:10.1001/jamaoncol.2020.1460 Key Points Question What are the costs of interventions leveraging social determinants of health to improve breast, cervical, and colorectal cancer screening, and are they cost-effective? Findings In this systematic review of 30 unique economic evaluations, the median intervention cost per participant was $123.87, the median incremental cost per additional person...

Trauma informed pain treatment

A patient-centered approach to opioid tapers must account for the reality that many people who are given a prescription for an opioid to treat pain have significant mental health conditions—for which opioids act as a psychotropic agent. An opioid taper must therefore address psychological trauma, in particular.

Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms (NEJM)

By Darshali A. Vyas, M.D., Leo G. Eisenstein, M.D., and David S. Jones, M.D., Ph.D., June 17, 2020, NEJM. Physicians still lack consensus on the meaning of race. When the Journal took up the topic in 2003 with a debate about the role of race in medicine, one side argued that racial and ethnic categories reflected underlying population genetics and could be clinically useful. 1 Others held that any small benefit was outweighed by potential harms that arose from the long, rotten history of...

Diagnosing and Treating Systemic Racism (NEJM)

June 10, 2020. Michele K. Evans, M.D., Lisa Rosenbaum, M.D., Debra Malina, Ph.D., Stephen Morrissey, h.D., and Eric J. Rubin, M.D., Ph.D. For the New England Journal of Medicine. For physicians, the words “I can’t breathe” are a primal cry for help. As many physicians have left their comfort zones to care for patients with Covid-19–associated respiratory failure, the role of the medical profession in addressing this life-defining need has rarely been clearer. But as George Floyd’s repeated...

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